Korea Brain Research Institute,
#501, Lab of Neurophysiology
61 Cheomdan-ro, Dong-gu,
Daegu 41062
South Korea
Lab of Cortical Neurophysiology


  • Kim E, Jeon S, Yang YS, Kin C, Kim JY, Oh YS, Rah JC*, Choi H*, A Neurospheroid-Based Microrobot for Targeted Neural Connections in a Hippocampal Slice, Advanced Materials 2023 Jan 14,
    *Corresponding authors
  • Kim YE*, Kim YS, Lee HE, Lee HE, So KH, Choe Y, Suh BC, Kim JH, Park SK, Mathern GW, Gleeson JG, Rah JC#, Baek ST#,
    Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway ,
    Cell Reports 2023 Jan 14;42(1):112003. doi: 10.1016/j.celrep.2023.112003. *equally contributed #Corresponding authors
  • Han YE*, Choi JH*, Kim K, Kang S, Park H, Choi JW, Jong-Cheol Rah,
    High-order thalamic and motor cortex inputs integrate sublinearly into tuft dendrites of pyramidal neurons in mouse somatosensory cortex, bioRxiv, 2022 Jul 6
    *equally contributed
  • Kim J, Lee J, Kim E, Choi JH, Jong-Cheol Rah* and Choi JW*,
    Dopamine depletion can be predicted by the aperiodic component of subthalamic local field potential
    Neurobiology of Disease, 2022 Mar 16;168:105692. Online ahead of print. doi: 10.1016/j.nbd.2022.105692.
    *Corresponding authors
  • Jong-Cheol Rah* and Joon Ho Choi*,
    Finding needles in a haystack with light: Resolving the microcircuit of the brain with fluorescence microscopy (Review),
    Molecules and Cells 2022 Feb; 45(2): 84-92. *Corresponding authors
    *Corresponding authors
  • Quaglio G, Toia P, Moser EI, Karapiperis T, Amunts K, Okabe S, Poo MM, Jong-Cheol Rah, Koninck Y, Ngai J, Richards L, Bjaalie JG.,
    The International Brain Initiative: enabling collaborative science,
    Lancet Neurol 2021 Dec;20(12):985-986. doi: 10.1016/S1474-4422(21)00389-6.
  • Kim G, Bahn S, Kim N, Choi JH, Kim JS and Jong-Cheol Rah
    Effective and accurate synapse detection with selective structured illumination microscopy on the putative regions of interest of ultrathin serial sections
    Frontiers in Neuroanatomy, 2021 Nov 15,
  • Yang YS, Choi JH and Jong-Cheol Rah
    Hypoxia with inflammation and reperfusion alters membrane resistance by dynamically regulating voltage-gated potassium channels in hippocampal CA1 neurons
    Molecular Brain, 2021 Sep 23;14(1):147. doi: 10.1186/s13041-021-00857-9.
  • Heo S, Ha J, Son SJ, Choi IS, Lee H, Oh S, Jekal J, Kang MH, Lee GJ, Jung HH, Yea J, Lee T, Lee Y, Choi JW, Xu S, Choi JH, Jeong JW, Song YM, Jong-Cheol Rah *, Keum H*, and Jang KI*, Instant, Multi-scale dry transfer printing by atomic diffusion control at heterogeneous interfaces
    Science Advances, 2021 Jul 09, Vol. 7, no.28, DOI: 10.1126/sciadv.abh0040
    *Corresponding authors
  • Kim NR, Bahn SK, Choi JH, Kim JS and Jong-Cheol Rah
    Synapses from the motor cortex and a high-order thalamic nucleus are spatially clustered in proximity to each other in the distal dendrites of the mouse somatosensory cortex
    Cerebral Cortex 2021 Aug 05 bhab236, DOI: 10.1093/cercor/bhab236
  • Kim S, Kang S, Kim J, Lee D, Kim S, Lee J, Jang KI, Oh YS, Jong-Cheol Rah, Huh MS, Paek SH, Choi JW
    Closed-Loop Neuromodulation for Parkinson’s Disease: Current State and Future Directions (review)
    IEEE Trans. Mol. Biol. Multi-Scale Commun, 7(4):209-223, 2020 Nov 09, doi: 10.1109/TMBMC.2020.3036756
  • Kim E, Jeon S, An HK, Kianpour M, Yu SW, Kim JY, Jong-Cheol Rah, Choi HS
    A magnetically actuated microrobot for targeted neural cell delivery and selective connection of neural networks
    Science Advances, 25 Sep 2020: Vol. 6, no. 39, eabb5696, DOI: 10.1126/sciadv.abb5696
  • Oh SW, Son SJ, Morris JA, Choi JH, Lee C, and Jong-Cheol Rah
    Comprehensive analysis of long-range connectivity from and to the posterior parietal cortex of the mouse
    Cereb Cortex. 2020 Sep 9:bhaa230. doi: 10.1093/cercor/bhaa230
  • Oh JY, Han JH, Lee H, Han YE, Jong-Cheol Rah, Park H
    Labeling Dual Presynaptic Inputs using cFork Anterograde Tracing System
    Exp Neurobiol 2020; 29(3):219-229.
  • Kang S, Noh HJ, Bae SH, Kim YS, Lew H, Lim J, Kim SJ, Hong KS, Jong-Cheol Rah*, Kim CH*
    Clozapine generates obsessive compulsive disorder-like behavior in mice
    Molecular Brain, 2020 May, 13:84.
    *corresponding authors
  • Lee JM, Choi JH, Jong-Cheol Rah
    Frequency-dependent gating of feedforward inhibition in thalamofrontal synapses
    Molecular Brain, 2020 May 6; 13: 68
  • Kim Y, Jang YN, Kim JY, Kim N, Noh S, Kim H, Queenan BN, Bellmore R, Mun JY, Park HJ, Jong-Cheol Rah, Park DT, Lee KJ
    Microtubule-associated Protein 2 Mediates Induction of Long-Term Potentiation in Hippocampal Neurons
    FASEB J, 2020 May;34(5):6965-6983. doi: 10.1096/fj.201902122RR
  • Yang YS, Son SJ, Choi JH, Jong-Cheol Rah
    Synaptic transmission and excitability during hypoxia with inflammation and reoxygenation in hippocampal CA1 neurons
    Neuropharmacology, 2018 May 25;138:20-31. doi: 10.1016/j.neuropharm.2018.05.011
  • Park SK, Ko SJ, Paik SK, Jong-Cheol Rah, Lee KJ, Bae YC
    Vesicular glutamate transporter 1 (VGLUT1)- and VGLUT2-immunopositive axon terminals on the rat jaw-closing and jaw-opening motoneurons
    Brain Struct Funct. 2018 Jun;223(5):2323-2334. doi: 10.1007/s00429-018-1636-y.
  • Bae JY, Lee JS, Ko SJ, Cho YS, Jong-Cheol Rah, Cho HJ, Park MJ, Bae YC
    Extrasynaptic homomeric glycine receptors in neurons of the rat trigeminal mesencephalic nucleus
    Brain Struct Funct. 2018 Jun;223(5):2259-2268. doi: 10.1007/s00429-018-1607-3. Epub 2018 Feb 19.
  • Han YE, Chun JN, Kwon MJ, Ji YS, Jeong MH, Kim HH, Park SH, Jong-Cheol Rah, Kang JS, Lee SH, Ho WK
    Endocytosis of KATP Channels Drives Glucose-Stimulated Excitation of Pancreatic b-Cells
    Cell Report, 2018 Jan 9; 22(2):471-481. doi: 10.1016/j.celrep.2017.12.049.
  • Jong-Cheol Rah
    Light-Microscopy-Based Sparse Neural Circuit Reconstruction: Array Tomography and Other Methods
    Applied Microscopy 2016;46:176-178
  • Jeong SJ, Lee H, Hur EM, Choe Y, Koo JW, Jong-Cheol Rah, Lee KJ, Lim HH, Sun W, Moon C, Kim K
    Korea Brain Initiative: Integration and Control of Brain Functions
    Neuron. 2016 Nov 2; 92(3):607-611. doi: 10.1016/j.neuron.2016.10.055.
  • Bae JY,Mah W, Jong-Cheol Rah, Park SK, Bae YC
    Expression of glycine receptor 3 in the rat trigeminal neurons and central boutons in the brain stem
    Brain Struct Funct 2016 Dec; 221(9):4601-4613
  • Jong-Cheol Rah, Feng L, Druckmann S and Kim J
    From meso- to microscale connectome: Array Tomography and mGRASP
    Front. Neuroanatomy 2015, 2015 Jun 4; 9:78.
  • Fortin DA, Tillo SE, Yang G, Jong-Cheol Rah, Melander JB, Bai S, Soler-Cedeno O, Qin M, Zemelman BV, Guo C, Mao T and Zhong H
    Live Imaging of Endogenous PSD-95 Using ENABLED: A Conditional Strategy to Fluorescently Label Endogenous Proteins
    J. Neurosci 2014, 34(50): 16698-712
  • Morita D., Jong-Cheol Rah, Isaac, JT
    Incorporation of Inwardly Rectifying AMPA receptors at Silent Synapses during Hippocampal LTP
    Phil. Trans. R. Soc. Lond. B. Biol Sci. 2014, 369: 20130156
  • Jong-Cheol Rah*, E Bas, J Colonell, Y Mishchenko, B Karsh, RD Fetter, EW Myers, DB Chklovskii, K Svoboda, TD Harris and JT Isaac
    Thalamocortical input onto layer 5 pyramidal neurons detected using quantitative large-scale array tomography
    Front. Neural Circuits. 2013. Nov 12; 7:177 *Corresponding author
  • Arancillo M, Min SW, Gerber SH, Agnieszka Munster-Wandowski, Wu YJ, Herman M, Trimbuch T, Jong-Cheol Rah, Ahnert-Hilger G, Riedel D, Sudhof TC, and Rosenmund C
    Titration of Syntaxin1 in mammalian synapses reveals multiple roles in vesicle docking, priming, and release probability
    J. Neurosci 2013. Oct 16;33(42):16698-714.
  • Gerber SH*, Jong-Cheol Rah*, Min SW*, Liu X, de Wit H, Dulubova I, Meyer AC, Rizo J, Arancillo M, Hammer RE, Verhage M, Rosenmund C, Sudhof TC
    Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
    Science. 2008 Sep 12; 321(5895): 1507-10
    *These authors contributed equally.
  • A Terashima*, KA Pelkey*, Jong-Cheol Rah, YH Suh, KW Roche, GL Collingridge, CJ McBain and JTR. Isaac
    An Essential Role for PICK1 in NMDA Receptor-Dependent Bidirectional Synaptic Plasticity
    Neuron. 2008 Mar 27; 57(6): 872-82.
  • L Li, OH Shin, JS Rhee, D Arac, Jong-Cheol Rah, J Rizo, TC Sudhof, C Rosenmund
    Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1
    J Biol Chem. 2006 Jun 9; 281(23): 15845-52.
  • JS Rhee, L Li, OH Shin, Jong-Cheol Rah, J Rizo, TC Sudhof, C Rosenmund
    Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1
    Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51): 18664-9.
  • CH Park, SH Choi, CH Kim, JH Seo, JW Koo, Jong-Cheol Rah, HS Kim, SJ Jeong, WS Joo, YJ Lee, YS Kim, MS Kim, YH Suh
    General pharmacology of indole [2',3':3,4]pyrido[2,1-b]quinazolinium-5,7,8,13-tetrahydro-14-methyl-5-oxo-chloride, a new anti-dementia agent
    Arzneimittelforschung. 2003; 53(6): 393-401.
  • JH Seo, Jong-Cheol Rah, SH Choi, JK Shin, K Min, HS Kim, CH Park, S Kim, EMKim, SH Lee, S Lee, SW Suh, YH Suh
    alpha-Synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway
    FASEB J. 2002 Nov, 16(13): 1826-8.
  • JH Kim, Jong-Cheol Rah, SP Fraser, KA Chang, MB Djamgoz, YH Suh
    Carboxyl-terminal peptide of beta-amyloid precursor protein blocks inositol 1,4,5-trisphosphate-sensitive Ca2+ release in Xenopus laevis oocytes
    J Biol Chem. 2002 Jun 7; 277(23): 20256-63.
  • Jong-Cheol Rah, HS Kim, SS Kim, JH Bach, SJ Jeong, JH Seo, CH Park, YS Kim, and YH Suh
    Effects of the carboxyl-terminal fragment of Alzheimer's amyloid precursor protein and amyloid beta-peptide on the production of cytokines and nitric oxide in glial cells
    FASEB J. 2001 Jun 15(8): 1463-1465.
  • JH Seo, KA Chang, HS Kim, CH Park, SH Kim, MJ Lee, SJ Jeong, SH Choi, Jong-Cheol Rah, J Koo, EM Kim, Y Xu, JH Choi, JK Shin, CJ Huh, L Kim, YH Suh
    Effects of Nicontine on Amyloid=beta or CT105-induced Toxicity, J Korean Brain Soc. 2001 June, 1:77-84.
  • JH Bach, HS Chae, Jong-Cheol RAH, MW Lee, SH Choi, JK Choi, YS Kim, KY Kim, WB Lee, YH Suh and SS Kim
    C-terminal fragment of Amyloid Precursor Protein induces Astrocytosis
    J Neurochem. 2001 Jul; 78(1):109-20
  • JH Seo, SH Kim, HS Kim, CH Park, SJ Jeong, JH Lee, SH Choi, KA Chang, Jong-Cheol Rah, JW Koo, EM Kim and YH Suh
    Effects of Nicotine on APP Secretion and Amyloid beta- or CT105-Induced Toxicity 2001
    Biol.Psychiatry 2001 Feb 1; 49(3): 240-7
  • HS Kim, CH Park, SH Cha, JH Lee, SW Lee, YM Kim, Jong-Cheol Rah, SJ Jeong and YH Suh
    C-terminal fragment of Alzheimer’s APP destabilize calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity
    FASEB J. 2000 Aug; 14(11): 1508-17.
  • SJ Jeong, HS Kim, CH Park, KA Chang, DH Geum, CH Pak, JH Seo, Jong-Cheol Rah, JH Lee, SH Choi, SG Lee and YH Suh
    Subcellular localization of presenilins during mouse preimplantation development
    FASEB J. 2000 Nov; 14(14): 2171-2176.
  • CH Park, SH Choi, Y Piao, SH Kim, YJ Lee, HS Kim, SJ Jeong, Jong-Cheol Rah, JH Seo, KA Chang, YJ Jung and YH Suh
    Glutamate and aspartate impair memory retenion and damage hypothalamic neurons in adult mice
    Toxicol Lett. 2000 May 19; 115(2): 117-25
  • YH Suh, HS Kim, JP Lee, CH Park, SJ Jeong, SS Kim, Jong-Cheol Rah, JH Seo, SS Kim
    Roles of Amyloid beta and carboxyl terminal peptide fragments of amyloid precursor protein in Alzheimer Disease (Review)
    J Neural Transm Suppl 2000;(58): 65-82.